Nurr1 agonist 4

Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC50 of 2.1 μM[1].

Product Specifications

CAS Number

[87645-58-7]

UNSPSC

12352005

Target

Nuclear Hormone Receptor 4A/NR4A

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nurr1-agonist-4.html

Purity

98.74

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=COC(C2=CC=C(OC)C=C2)=C1)O

Molecular Formula

C12H10O4

Molecular Weight

218.21

References & Citations

[1]Marco Ballarotto, et al. De Novo Design of Nurr1 Agonists via Fragment-Augmented Generative Deep Learning in Low-Data Regime. J Med Chem. 2023 Jun 22;66 (12) :8170-8177.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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