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LCL521 dihydrochloride

Product Specifications

UNSPSC Description

LCL521 dihydrochloride is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase)[1].

Target Antigen

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/LCL521_dihydrochloride.html

Purity

98.12

Solubility

DMSO : 20.83 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(CN(C)C)O[C@H](C1=CC=C([N+]([O-])=O)C=C1)[C@@H](COC(CN(C)C)=O)NC(CCCCCCCCCCCCC)=O.[H]Cl.[H]Cl

Molecular Weight

665.69

References & Citations

[1]Bai A, et al. Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs. Bioorg Med Chem. 2014 Dec 15;22(24):6933-44.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-103593A/LCL521-dihydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-103593A/LCL521-dihydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1226759-47-2

Available Sizes

Curated Selection

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