2-Aminoacetamide hydrochloride

2-Aminoacetamide hydrochloride (Glycinamide hydrochloride) is a derivative of Glycine (HY-Y0966) . 2-Aminoacetamide hydrochloride forms cell-absorbable nanocomplexes with proteins (such as bovine serum albumin) through strong electrostatic interactions, promoting cellular uptake of related proteins. 2-Aminoacetamide hydrochloride synergizes with BMP2 to upregulate the expression of osteogenic marker genes (such as Col1a1, Alp, Runx2) and proteins (such as COL1, BSP), enhancing collagen synthesis. 2-Aminoacetamide hydrochloride synergizes with BMP2 to promote osteoblast differentiation in vitro and bone regeneration in vivo[1].

Product Specifications

CAS Number

[1668-10-6]

Product Name Alternative

Glycinamide hydrochloride

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives; Phosphatase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/2-aminoacetamide-hydrochloride.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N)CN.Cl

Molecular Formula

C2H7ClN2O

Molecular Weight

110.54

Precautions

H302, H315, H319, H335

References & Citations

[1]Nam SH, et al. Glycinamide Facilitates Nanocomplex Formation and Functions Synergistically with Bone Morphogenetic Protein 2 to Promote Osteoblast Differentiation In Vitro and Bone Regeneration in a Mouse Calvarial Defect Model. Tissue Eng Regen Med. 2024 Oct;21 (7) :1093-1107.