Dicloromezotiaz

Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs) . Dicloromezotiaz can be used to control a broad range of lepidoptera[1].

Product Specifications

CAS Number

[1263629-39-5]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dicloromezotiaz.html

Purity

98.65

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

O=C1[C-](C2=CC(Cl)=CC(Cl)=C2)C([N+](CC3=CN=C(Cl)S3)=C4C(C)=CC=CN14)=O

Molecular Formula

C19H12Cl3N3O2S

Molecular Weight

452.74

Precautions

H315, H319, H335

References & Citations

[1]Montgomery M, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators [published correction appears in J Med Chem. 2022 Mar 10;65 (5) :4401-4402]. J Med Chem. 2022;65 (3) :2297-2312.