Dicloromezotiaz
Dicloromezotiaz is a potent insecticide acting on nicotinic acetylcholine receptors (nAChRs) . Dicloromezotiaz can be used to control a broad range of lepidoptera[1].
Product Specifications
CAS Number
[1263629-39-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dicloromezotiaz.html
Purity
98.65
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C1[C-](C2=CC(Cl)=CC(Cl)=C2)C([N+](CC3=CN=C(Cl)S3)=C4C(C)=CC=CN14)=O
Molecular Formula
C19H12Cl3N3O2S
Molecular Weight
452.74
Precautions
H315, H319, H335
References & Citations
[1]Montgomery M, et al. Structural Biology-Guided Design, Synthesis, and Biological Evaluation of Novel Insect Nicotinic Acetylcholine Receptor Orthosteric Modulators [published correction appears in J Med Chem. 2022 Mar 10;65 (5) :4401-4402]. J Med Chem. 2022;65 (3) :2297-2312.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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