BAY 73-1449
BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG. BAY 73-1449 can be used in the research of lowering blood pressure[1].
Product Specifications
CAS Number
[693790-96-4]
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bay-73-1449.html
Purity
99.99
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)[C@@H](CC1=CC=CC=C1)NC2=NC=NC(C3=CC=C(OCC4=CC=CC=C4)C=C3)=C2
Molecular Formula
C26H23N3O3
Molecular Weight
425.48
References & Citations
[1]Bexis S, et, al. Vascular actions of the prostacyclin receptor antagonist BAY 73-1449 in the portal hypertensive rat. Eur J Pharmacol. 2008 Aug 20;590 (1-3) :322-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IP
Available Sizes
Curated Selection
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