17α-Hydroxyprogesterone

17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension[1][2].

Product Specifications

CAS Number

[68-96-2]

Product Name Alternative

17-Hydroxyprogesterone; 17-OHP

UNSPSC

12352211

Hazard Statement

H360

Target

Endogenous Metabolite; Progesterone Receptor

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/17-Hydroxyprogesterone.html

Purity

99.96

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

CC([C@@]1(O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O

Molecular Formula

C21H30O3

Molecular Weight

330.46

Precautions

H360

References & Citations

[1]Reddy P R, et al. 17α-Hydroxyprogesterone induced ovarian growth and vitellogenesis in the freshwater rice field crab Oziotelphusa senex senex. Aquaculture, 2006, 254 (1-4) : 768-775.|[2]Coghlan J P, et al. Hypertensive effect of 17α, 20α7–dihydroxyprogesterone and 17α-hydroxyprogesterone in the sheep. Nature, 1976, 263 (5578) : 608-609.