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2,5-Dihydroxyacetophenone

2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways[1].

Product Specifications

CAS Number

490-78-8

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ERK; NF-κB

Type

Natural Products

Related Pathways

MAPK/ERK Pathway; NF-κB; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html

Concentration

10mM

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC(O)=CC=C1O)=O

Molecular Formula

C8H8O3

Molecular Weight

152.15

Precautions

H302, H315, H319, H335

References & Citations

Rehmanniae Radix

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

ERK1; ERK2; NF-κB

Available Sizes

Frequently Asked Questions

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