2,5-Dihydroxyacetophenone
2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling pathways[1].
Product Specifications
CAS Number
[490-78-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ERK; NF-κB
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; NF-κB; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-5-dihydroxyacetophenone.html
Concentration
10mM
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC(O)=CC=C1O)=O
Molecular Formula
C8H8O3
Molecular Weight
152.15
Precautions
H302, H315, H319, H335
References & Citations
Rehmanniae Radix
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; NF-κB
Available Sizes
Curated Selection
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