β-Zearalanol-d4
Product Specifications
UNSPSC Description
β-Zearalanol-d4 is a deuterium labeled Beta-Zearalanol (HY-N6740）[1]. Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells[2]. Beta-Zearalenol is the derivative of zearalenone (ZEA) which can conjugate with glucuronic acid[3].
Target Antigen
Apoptosis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis;Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
OC1=C2C(/C=C/CCC([2H])([2H])[C@@H](C([2H])([2H])CC[C@@H](OC2=O)C)O)=CC(O)=C1
Molecular Weight
324.40
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.|[2]Yang F, et al. Melatonin alleviates β-zearalenol and HT-2 toxin-induced apoptosis and oxidative stress in bovine ovarian granulosa cells. Environ Toxicol Pharmacol. 2019 May;68:52-60.|[3]Marin DE, et al. Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites. Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug;392(8):937-947.
Shipping Conditions
Room temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Clinical Information
No Development Reported
CAS Number
1778735-09-3
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