CDK9-IN-35
CDK9-IN-35 (compound 10j) is an inhibitor of CDK9/Cyclin T1 with an IC50 value of 10.2 nM and against the HCT-116 cell line with an IC50 value of 20 nM[1].
Product Specifications
UNSPSC
12352211
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk9-in-35.html
Smiles
COC1=C(N=C(N=C1)NC2=CC=C(C(Cl)=C2)OCC3=CC=CC(F)=C3)NCC4=CC=C(C=C4)S(C)(=O)=O
Molecular Formula
C26H24ClFN4O4S
Molecular Weight
543.01
References & Citations
[1]Gopalakrishnan Venkatesan, et al. Design, synthesis, molecular modeling and evaluation of 2,4-diaminopyrimidine analogues as promising colorectal cancer drugs. Bioorg Chem. 2024 Sep 29:153:107854.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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