MAGL-IN-14
MAGL-IN-14 (compound 2) is a potent inhibitor of MAGL, with IC50 of 0.00289 μM and 0.002 μM in HEK293 and PC3 cells, respectively[1].
Product Specifications
CAS Number
2770967-04-7
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/magl-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1CC12CCN(C(OC(C(F)(F)F)C(F)(F)F)=O)CC2)NC3=CC=CN=C3
Molecular Formula
C17H17F6N3O3
Molecular Weight
425.33
References & Citations
[1]H. Lundbeck A/S. Preparation of ubstituted 1,1,1,3,3,3-hexafluoropropan-2-yl 6-azaspiro[2.5]octane-6-carboxylates as MAGL inhibitors. World Intellectual Property Organization, WO2022101412 A1 2022-05-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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