Neamine
Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities[1][2].
Product Specifications
CAS Number
3947-65-7
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/neamine.html
Purity
99.96
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O[C@H]([C@H]1O)[C@@H]([C@H](C[C@H]1N)N)O[C@H]([C@@H]([C@H]2O)N)O[C@@H]([C@H]2O)CN
Molecular Formula
C12H26N4O6
Molecular Weight
322.36
Precautions
H315, H319
References & Citations
[1]Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36 (1) :82-87.|[2]R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aminoglycoside
Available Sizes
Frequently Asked Questions
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