Neamine

Neamine, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine is an anti-angiogenesis agent targeting angiogenin. Neamine has potent antibacterial, antitumor and neuroprotective activities[1][2].

Product Specifications

CAS Number

[3947-65-7]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/neamine.html

Purity

99.96

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H]1O)[C@@H]([C@H](C[C@H]1N)N)O[C@H]([C@@H]([C@H]2O)N)O[C@@H]([C@H]2O)CN

Molecular Formula

C12H26N4O6

Molecular Weight

322.36

Precautions

H315, H319

References & Citations

[1]Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36 (1) :82-87.|[2]R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85.