Human Collagen Type III, Lyophilized

Human Collagen Type III protein purified from human placenta. Type III collagen is a fibrillar collagen, and it consists of only one collagen α chain, in contrast to most other collagens....

Product Specifications

Background

Human Collagen Type III protein purified from human placenta. Type III collagen is a fibrillar collagen, and it consists of only one collagen α chain, in contrast to most other collagens. It is a homotrimer containing three α1 (III) chains supercoiled around each other in a right-handed triple helix. Type III collagen is secreted by fibroblasts and other mesenchymal cell types, thus making it a major player in various inflammation-associated pathologies such as lung injury, viral and nonviral liver diseases, kidney fibrosis, hernia, and vascular disorders. Type III collagen together with type I collagen are the main constituents of the interstitial matrix.

Short Description

Human Collagen Type III, Lyophilized 0.1 mg

Source

Human placenta

Purification

Partial pepsin digestion in acidic conditions and differential salt precipitation.

Assay Type

Protein

Purity

Human Collagen Type II 90%

Form

Lyophilized, 0.1 mg/vial

Reconstitution

Use 0.5 M acetic acid, pH 2.5

Storage Conditions

Collagen dissolved in acetic acid is stable at 4 °C for 1 month. Lyophilized collagen long term storage (2 years) at -20°C or lower.

Related Products

Bovine Collagen Type VI, Lyophilized, 0.1mg; Collagen Type I (Atelocollagen) Porcine, 30 mg; Collagen Type I (Atelocollagen), Bovine, 30 mg; Collagen Type I (Atelocollagen), Mouse, 1 mg; Collagen Type I (Atelocollagen), Rat, 30 mg