Collagen Type I, Mouse
Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. Type I collagen is the most abundant collagen and is found in...
Product Specifications
Background
Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligament, dermis and blood vessel. It is the major component and the primary determinant of tensile strength of the extracelluar matrix (ECM) . It is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells etc. In addition, collagen I can self-assemble into a 3-D superamolecular gel in vitro, making it an ideal biological scaffold to promote more in vivo-like cellular morphology and function. Symbols/Related Terms: COL1A1 COL1A2 osteogenesis imperfecta
Short Description
Collagen Type I, Mouse, 1 mg
Source
Mouse tail tendon
Purification
Partial pepsin digestion in acidic conditions and differential salt precipitation.
Assay Type
Protein
Form
Lyophilized, 1 mg/vial
Reconstitution
Add 0.01-0.05 M acetic acid to yield 1-5 mg/mL collagen solution. Gentle mixing overnight at 4°C.
Storage Conditions
Collagen dissolved in acetic acid is stable at 4 °C for 1 month. Lyophilized collagen long term storage (2 years) at -20°C or lower.
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Collagen Type I (Atelocollagen) Porcine, 30 mg; Collagen Type I (Atelocollagen), Bovine, 30 mg; Collagen Type I (Atelocollagen), Mouse, 1 mg; Collagen Type I (Atelocollagen), Rat, 30 mg; Collagen Type I and III, Bovine, 10 mg
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