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Collagen Type I, Mouse

Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. Type I collagen is the most abundant collagen and is found in...

Product Specifications

Background

Purified type I native mouse collagen from mouse tail tendon. Lyophilized. Reconstitute to yield 1-5 mg/mL collagen solution. Type I collagen is the most abundant collagen and is found in connective tissues including tendon, ligament, dermis and blood vessel. It is the major component and the primary determinant of tensile strength of the extracelluar matrix (ECM) . It is widely used as a thin layer on tissue-culture surfaces to enhance the attachment and proliferation of a variety of cells including endothelial cells, fibroblasts, hepatocytes, epithelial cells etc. In addition, collagen I can self-assemble into a 3-D superamolecular gel in vitro, making it an ideal biological scaffold to promote more in vivo-like cellular morphology and function. Symbols/Related Terms: COL1A1 COL1A2 osteogenesis imperfecta

Short Description

Collagen Type I, Mouse, 1 mg

Source

Mouse tail tendon

Purification

Partial pepsin digestion in acidic conditions and differential salt precipitation.

Assay Type

Protein

Form

Lyophilized, 1 mg/vial

Reconstitution

Add 0.01-0.05 M acetic acid to yield 1-5 mg/mL collagen solution. Gentle mixing overnight at 4°C.

Storage Conditions

Collagen dissolved in acetic acid is stable at 4 °C for 1 month. Lyophilized collagen long term storage (2 years) at -20°C or lower.

Related Products

Collagen Type I (Atelocollagen) Porcine, 30 mg; Collagen Type I (Atelocollagen), Bovine, 30 mg; Collagen Type I (Atelocollagen), Mouse, 1 mg; Collagen Type I (Atelocollagen), Rat, 30 mg; Collagen Type I and III, Bovine, 10 mg

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