Activin A Recombinant Protein (Human)

The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa) . Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune and inflammatory responses, cell death, and has a neurotrophic function crucial for brain repair. Produced by many cell types, Activin A is a disulfide-linked homodimer that binds to type I and type II serine-threonine kinase receptors, primarily signaling through SMAD2/3 proteins. This signaling regulates cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A plays a critical role in neuroprotection and adult neurogenesis, particularly following brain damage, by regulating spine formation and promoting neurogenesis.

PD1 (PDCD1, CD279), Active, Recombinant Protein, Human, 20ug; CD80 (CTLA-4 / B7-1) Recombinant Protein, Human, 5ug; CD86 (CTLA-4 / B7-2) Recombinant Protein, Human, 20ug; Galectin-9 (LGALS9) Recombinant Protein, Human, 10ug; TIGIT Recombinant Protein, Human, 10ug