Activin A Recombinant Protein (Human)
The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa) . Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune...
Product Specifications
Background
The human Activin A recombinant protein consists of a non-glycosylated polypeptide chain containing 137 amino acids (311-426aa) . Activin A, a member of the transforming growth factor beta (TGF-β) superfamily, regulates immune and inflammatory responses, cell death, and has a neurotrophic function crucial for brain repair. Produced by many cell types, Activin A is a disulfide-linked homodimer that binds to type I and type II serine-threonine kinase receptors, primarily signaling through SMAD2/3 proteins. This signaling regulates cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A plays a critical role in neuroprotection and adult neurogenesis, particularly following brain damage, by regulating spine formation and promoting neurogenesis.
Short Description
Activin A Recombinant Protein (Human), 10ug
Volume
10μg / vial
Assay Type
Cell Signaling Pathways
Purity
> 95%, as determined by SDS-PAGE
Form
Soluble
Buffer
This protein is supplied in 20mM Tris (pH 8.0) and 10% glycerol.
Molecular Weight
15.2kDa
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Host or Source
E.coli
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