PD-L2 (CD273) Recombinant Protein, Human

Product Specifications

Background

The human Programmed cell death 1 ligand 2 (PD-L2) / CD273 is a recombinant protein consists of a single non-glycosylated polypeptide chain with 204 amino acids (20-200aa) . Programmed cell death-1 (PD-1) is a key immunosuppressive molecule with two known ligands, PD-L1 and PD-L2. PD-L2 (also known as B7-DC or CD273), encoded by the PDCD1LG2 gene, plays a role in the negative regulation of the adaptive immune response as an immune checkpoint receptor ligand. Both PD-L1 and PD-L2 interact with PD-1 to modulate immune responses, making them significant targets in immunotherapy studies aimed at enhancing anti-tumor activity. Abbreviations: bA574F11.2, Butyrophilin B7-DC, PDCD1LG2, Btdc, PDCD1 ligand 2, PD-L2, Programmed death ligand 2, PDL2, PD-1 ligand 2, B7-DC, CD273, CD273, PDCD1L2, PD-L2.

Short Description

PD-L2 (CD273) Recombinant Protein, Human, 20ug

Volume

20μg / vial

Assay Type

Cell Signaling Pathways

Concentration

1.0 mg/mL (Refer to the vial label for the concentration.)

Purity

> 95%, as determined by SDS-PAGE

Form

Soluble

Buffer

This protein is supplied in 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea, and 10% glycerol.

Molecular Weight

22.8kDa

Storage Conditions

Stable at 4°C for one month or stored in the dark at -20°C long-term.

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