Anti-PI3 Kinase, p85 (C-terminal region) Antibody

Our PI3 Kinase, p85 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat PI3 Kinase, p85 (C-terminal region) and is protein a purified. It is great for use in ELISA, WB, ICC.

Product Specifications

Background

Phosphoinositide 3-kinase (PI3K) phosphorylates phosphatidylinositol (PI), PI-4-phosphate and PI-4,5-bisphosphate to catalyze the production of PI-3,4,5-triphosphate. Growth factors and hormones activate PI3K to coordinate various cellular events, such as cell growth, cell cycle entry, cell migration and cell survival. This PI3K activation is reversed by PTEN. In cancers caused by the loss of PTEN activity, PI3K is constituitively active and promotes cell proliferation. PI3Ks are composed of a catalytic subunit and a regulatory subunit. Various isoforms of the catalytic subunit (p110a, p110b and p110d) associate with regulatory subunits (p85a and p85b) with the exception of p110g which interacts with a unique p101 regulatory subunit.

Short Description

Our PI3 Kinase, p85 (C-terminal region) primary antibody from PhosphoSolutions is mouse monoclonal. It detects chicken, human, mouse, and rat PI3 Kinase, p85 (C-terminal region) and is Protein A purified. It is great for use in WB, ICC.

Synonyms

PI3K

Gene Name

PIK3R1

UniProt

P27986

Reactivity

Chicken, Human, Mouse, and Rat

Immunogen

Clone M253 was generated from a recombinant protein corresponding to amino acids in the C-terminal region of human PI3 Kinase α subunit. This region is homologous to similar regions in rat and mouse PI3 Kinase α subunit.

Target

PI3 Kinase, p85 (C-terminal region)

Clonality

Monoclonal

Clone

M253

Conjugation

Unconjugated

Applications

ELISA, WB, ICC

Field of Research

Cell Signaling, Kinase Signaling, Oncoproteins

Format

Protein A Purified

Buffer

PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol

Modification

GOmAb

Molecular Weight

Precautions

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Shipping Conditions

Blue Ice

Storage Conditions

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.