5-Bromopentanoyl chloride

5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs[1].

Product Specifications

CAS Number

[4509-90-4]

UNSPSC

12352211

Hazard Statement

H314, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-bromopentanoyl-chloride.html

Purity

98.94

Solubility

10 mM in DMSO

Smiles

O=C(Cl)CCCCBr

Molecular Formula

C5H8BrClO

Molecular Weight

199.47

Precautions

H314, H335

References & Citations

[1]Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63 (17) :e202318568.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

P522057 100 µg

AK4 Protein (N-cleavage, Human)

View Details

MBS7101298 Inquire

Recombinant Halobacterium salinarum Preprotein translocase subunit SecE (secE), partial

View Details

sc-339476A 1 g

2- (2-Chloro-acetylamino) -5,6-dihydro-4H-thieno[2,3-b]thiopyran-3-carboxylic acid ethyl ester

View Details

MR206639L3 10 µg

Sgms1 (NM_144792) Mouse Tagged Lenti ORF Clone

View Details

RDC3592 10 µg

Human IFN-alpha B2/IFNA8 (NP_002161.2) VersaClone cDNA

View Details

KN517758 1 Kit

Tmem174 Mouse Gene Knockout Kit (CRISPR)

View Details