5-Bromopentanoyl chloride
Product Specifications
UNSPSC Description
5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-bromopentanoyl-chloride.html
Purity
98.63
Solubility
10 mM in DMSO
Smiles
O=C(Cl)CCCCBr
Molecular Weight
199.47
References & Citations
[1]Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63(17):e202318568.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-43538/5-Bromopentanoyl-chloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-43538/5-Bromopentanoyl-chloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
4509-90-4
Available Sizes
Curated Selection
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