5-Bromopentanoyl chloride

5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs[1].

Product Specifications

CAS Number

[4509-90-4]

UNSPSC

12352211

Hazard Statement

H314, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-bromopentanoyl-chloride.html

Purity

98.94

Solubility

10 mM in DMSO

Smiles

O=C(Cl)CCCCBr

Molecular Formula

C5H8BrClO

Molecular Weight

199.47

Precautions

H314, H335

References & Citations

[1]Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63 (17) :e202318568.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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