5-Bromopentanoyl chloride
5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs[1].
Product Specifications
CAS Number
[4509-90-4]
UNSPSC
12352211
Hazard Statement
H314, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-bromopentanoyl-chloride.html
Purity
98.94
Solubility
10 mM in DMSO
Smiles
O=C(Cl)CCCCBr
Molecular Formula
C5H8BrClO
Molecular Weight
199.47
Precautions
H314, H335
References & Citations
[1]Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63 (17) :e202318568.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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