HYOU1-IN-1

HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1-IN-1 can be used in research on the regulation of fibroblast activation, chronic inflammation, and fibrotic diseases[1].

Product Specifications

CAS Number

[2832155-52-7]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hyou1-in-1.html

Purity

98.32

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NCC1(NC2=CC=C(Cl)C=C2)CCCCCC1)C3=CC(Cl)=C(N)C=C3OC

Molecular Formula

C22H27Cl2N3O2

Molecular Weight

436.37

References & Citations

[1]Papadopoulou D, et al. Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation. Angew Chem Int Ed Engl. 2024 Feb 10:e202319157.