HYOU1-IN-1
HYOU1-IN-1 (Compound 33) is an inhibitor of hypoxia-upregulated protein 1 (HYOU1) with anti-inflammatory activity. HYOU1-IN-1 can be used in research on the regulation of fibroblast activation, chronic inflammation, and fibrotic diseases[1].
Product Specifications
CAS Number
[2832155-52-7]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hyou1-in-1.html
Purity
98.32
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NCC1(NC2=CC=C(Cl)C=C2)CCCCCC1)C3=CC(Cl)=C(N)C=C3OC
Molecular Formula
C22H27Cl2N3O2
Molecular Weight
436.37
References & Citations
[1]Papadopoulou D, et al. Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation. Angew Chem Int Ed Engl. 2024 Feb 10:e202319157.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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M2865-11F 10 Blots
MEK1, phosphorylated (Thr386) (MAPK/ERK Kinase 1, MEK 1, Dual Specificity Mitogen-Activated Protein Kinase Kinase 1, MAP Kinase Kinase 1, MAP2K1, MAPKK 1, MKK1, PRKMK1, ERK Activator Kinase 1)
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