AM-9022
AM-9022 is an orally active, potent, selective KIF18A inhibitor that can be used for research on cancer[1].
Product Specifications
CAS Number
[2446872-46-2]
UNSPSC
12352005
Target
Kinesin; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/am-9022.html
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(NS([C@H](C)CO)(=O)=O)C=C1N2CCC3(CC3)CC2)NC4=CC(C)=NC(N5CCC(F)(F)CC5)=N4
Molecular Formula
C27H36F2N6O4S
Molecular Weight
578.67
References & Citations
[1]Payton M, et al. Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers. Nat Cancer. 2023 Dec 27.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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