Trimebutine (3-TCBS)
Trimebutine 3-TCBS (GIC-1001) is an innovative formulation designed to release hydrogen sulfide (H2S) in vivo. This compound combines trimebutine with an H2S-releasing antagonist (phenyl 3-thiocarbamate) and exhibits enhanced anti-nociceptive effects in a mouse colonic distension model, superior to conventional trimebutine. GIC-1001 can reduce visceral pain and discomfort associated with lumen distension in a dose-dependent manner, showing potential superiority[1].
Product Specifications
CAS Number
1456509-46-8
Product Name Alternative
GIC-1001
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/trimebutine-3-tcbs.html
Smiles
O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCC(N(C)C)(CC)C2=CC=CC=C2.O=S(C3=CC=CC(C(N)=S)=C3)(O)=O
Molecular Formula
C29H36N2O8S2
Molecular Weight
604.73
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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