Benzamide (Standard)

Benzamide (Standard) is the analytical standard of Benzamide. This product is intended for research and analytical applications. Benzamide (Benzenecarboxamide) is a potent poly (ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH) -induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

Product Specifications

CAS Number

[55-21-0]

Product Name Alternative

Benzenecarboxamide (Standard) ; Phenylamide (Standard)

UNSPSC

12352005

Hazard Statement

H302, H341

Target

Endogenous Metabolite; PARP; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/benzamide-standard.html

Smiles

NC(C1=CC=CC=C1)=O

Molecular Formula

C7H7NO

Molecular Weight

121.14

Precautions

H302, H341

References & Citations

[1]Cosi C, et al. Benzamide, an inhibitor of poly (ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996 Oct 7;735 (2) :343-8.