Flagellin
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system via Toll-like receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4) . Source: Recombinant Flagellin from Salmonella typhimurium Endotoxin level: <0.5 EU/μg Specificity: TLR5 agonist
Product Specifications
Product Name Alternative
FliC
Reactivity
Mouse, Human
Applications
Functional Assay
Components
0.1 mg/ml in endotoxin-free water
Storage Conditions
Upon receipt, store at -20°C (Stable for at least 6 months) . Avoid frequent freeze/thaw cycles.
Applications Notes
TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1μg /mouse.
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