Niazinin
Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity[1][2].
Product Specifications
CAS Number
147821-57-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Parasite; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/niazinin.html
Purity
99.94
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1OC2=CC=C(C=C2)CNC(OC)=S
Molecular Formula
C15H21NO6S
Molecular Weight
343.40
Precautions
H302, H315, H319
References & Citations
[1]Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69 (3-4) :110-6.|[2]Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania
Available Sizes
Frequently Asked Questions
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