Niazinin

Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity[1][2].

Product Specifications

CAS Number

[147821-57-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Parasite; SARS-CoV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/niazinin.html

Purity

99.94

Solubility

DMSO : ≥ 50 mg/mL

Smiles

O[C@H]([C@@H]([C@H]([C@@H](O1)C)O)O)[C@@H]1OC2=CC=C(C=C2)CNC(OC)=S

Molecular Formula

C15H21NO6S

Molecular Weight

343.40

Precautions

H302, H315, H319

References & Citations

[1]Amandeep Kaur, et al. Antileishmanial compounds from Moringa oleifera Lam. Z Naturforsch C J Biosci. Mar-Apr 2014;69 (3-4) :110-6.|[2]Shiv Rakesh Naik, et al. Structure-based virtual screening, molecular dynamics and binding affinity calculations of some potential phytocompounds against SARS-CoV-2. J Biomol Struct Dyn. 2021 Mar 8;1-18.