Recombinant anti-human-Amyloid Beta Antibody (Lecanemab Biosimilar)
Target: Amyloid Beta Generic name: Lecanemab Product Origin: Recombinant in Human cells People with Alzheimerâ€TMs disease have a protein called amyloid that continuously builds up in the brain. It starts with small forms of amyloid protein. These may clump together into larger forms, which can damage the brain cells. As they continue to build up, they can form harmful amyloid brain plaques. Lecanemab is humanized monoclonal antibodies targeting cerebral amyloid-beta (A-2) plaques. References: 1. Panza F, Lozupone M, Logroscino G, Imbimbo BP. A critical appraisal of amyloid--2-targeting therapies for Alzheimer disease. Nat Rev Neurol. 2019;15 (2) :73-88..
Product Specifications
Product Name Alternative
Amyloid beta, Lecanemab
Gene Name
Amyloid
Gene ID
620
UniProt
P05067
Reactivity
Human
Clonality
Monoclonal
Applications
Functional Assay, ELISA, ICC/IF, FACS
Purification
Purified from cell culture supernatant by affinity chromatography
Format
Purified
Components
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.Sterile
Storage Conditions
Store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Specificity: Human Amyloid beta. Inquire for more than 1 mg quantities.
Isotype
Human IgG1
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