Anti-Human CD52 (Alemtuzumab) Biotin

Expression Host : HEK-293 This non-therapeutic biosimilar antibody uses the same variable region sequence as the therapeutic antibody Alemtuzumab. Clone Campath-1H recognizes human CD52. This product is for research use only. Clone Campath-1H is a monoclonal antibody that specifically binds to CD52, a protein present on the surface of mature lymphocytes. However, this protein is not present on the stem cells that generated these lymphocytes. Alemtuzumab is targets and destroys mature lymphocytes containing CD-52, and is used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. Anti-Human CD52 (Alemtuzumab) utilizes the same variable regions from the therapeutic antibody Alemtuzumab making it ideal for research projects.

Product Specifications

Product Name Alternative

HE5; CDW52; EDDM5 CDW52; Cambridge pathology 1 antigen

Host

Human

Immunogen

Human lymphocytes.

Target Antigen

CD52

Clonality

Monoclonal

Clone

Campath-1H

Applications

ELISA

Components

Concentration : 0.5 mg/mlThis Biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

Storage Conditions

This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.

Applications Notes

The suggested concentration for Alemtuzumab biosimilar antibody for staining cells in flow cytometry is <= 1.0 μg per 106 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application.