Human EPHA3 (21-324) Protein, His Tag

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]Molecular Weight : The protein has a predicted molecular mass of 36.0 kDa after removal of the signal peptide. The apparent molecular mass of EPHA3 (21-324) -His is approximately 35-55 kDa due to glycosylation.Tag :C-10?His tag

Product Specifications

Product Name Alternative

EK4; ETK; HEK; ETK1; HEK4; TYRO4, Recombinant human EPHA3 (21-324) Protein with C-terminal 10?His tag

Gene Name

EPHA3

UniProt

P29320

Host

HEK293

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.