Human GPA33 (135-235) Protein, hFc Tag

The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319-amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily. [provided by RefSeq, Jul 2008]Molecular Weight : The protein has a predicted molecular mass of 37.1 kDa after removal of the signal peptide. The apparent molecular mass of GPA33 (135-235) -hFc is approximately 35-55 kDa due to glycosylation.Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

A33, Recombinant human GPA33 (135-235) Protein with C-terminal human Fc tag

Gene Name

GPA33

UniProt

Q99795

Host

HEK293

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.