IL-1beta (human) (Recombinant) (untagged)
Source :E. coli Specific Binds to human IL-1R.IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
Product Specifications
Product Name Alternative
Interleukin-1beta; IL-1F2
Reactivity
Human
Applications
Functional Assay
Purification
>=95% (SDS-PAGE)
Components
Reconstitute with 100μl sterile water.0.1mg/mL after reconstitution. Lyophilized. Contains PBS.
Storage Conditions
Applications Notes
Biological Activity: Activates the NF-kB with an ED50 of <5ng/ml. Endotoxin Content <0.1EU/μg purified protein (LAL test; Lonza) .
Amino Acids
Human IL-1beta (aa 117-269) is untagged.
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