IL-6 (human) :Fc (human) (Recombinant)

Source :CHO cells Specific Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130) . IL-6 is a key factor for the growth of plasma cells.

Product Specifications

Product Name Alternative

Interleukin-6; B Cell Stimulatory Factor 2; BSF-2; CTL Differentiation Factor; CDF; Interferon beta2; IFN-beta2

Reactivity

Human

Applications

Functional Assay

Purification

>=98% (SDS-PAGE)

Components

Reconstitute 50μg vial in 50μl sterile water. Add 1X PBS to the desired protein concentration. Lyophilized from 0.2μm-filtered solution in PBS.

Storage Conditions

Short Term Storage +4°C ; Long Term Storage-20°C ; Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.