Mouse IGF-1R Protein, His Tag

Description :Recombinant mouse IGF-1R protein with C-terminal6Ã-His tagBackground : Enables insulin-like growth factor binding activity. Involved in several processes, including adrenal gland development; positive regulation of cold-induced thermogenesis; and positive regulation of meiotic cell cycle. Acts upstream of or within several processes, including gland development; peptidyl-tyrosine autophosphorylation; and regulation of intracellular signal transduction. Located in T-tubule. Is integral component of membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and lung. Human ortholog (s) of this gene implicated in several diseases, including dementia (multiple) ; kidney cancer (multiple) ; liver disease (multiple) ; nervous system cancer (multiple) ; and neurodegenerative disease (multiple) . Orthologous to human IGF1R (insulin like growth factor 1 receptor) . Molecular Characterization: mass of 104.5 kDa after removal of the signal peptide.Tag :C-6Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

Hyft; CD221; IGF1R

UniProt

Q60751

Host

HEK293

Target Antigen

IGF-1R

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.