Mouse AXL Protein, His Tag

Description :Recombinant mouse AXL protein with C-terminal 10Ãƒâ€”His tagBackground : Predicted to enable several functions, including phosphatidylinositol 3-kinase binding activity; phosphatidylserine binding activity; and virus receptor activity. Involved in negative regulation of apoptotic process and positive regulation of protein kinase B signaling. Acts upstream of or within several processes, including animal organ development; myeloid cell homeostasis; and negative regulation of tumor necrosis factor production. Predicted to be located in several cellular components, including actin cytoskeleton; cell surface; and host cell surface. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and visual system. Human ortholog (s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human AXL (AXL receptor tyrosine kinase) . Molecular Characterization: mass of 47.8 kDa after removal of the signal peptide. The apparent molecular mass of mAXL-His is approximately 55-70 kDa due to glycosylation.Tag :C-10Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

Ark; Ufo; Tyro7

UniProt

Q00993

Host

HEK293

Target Antigen

AXL

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.