Mouse TNFRSF1B Protein, His Tag

Description :Recombinant mouse TNFRSF1B protein with C-terminal6Ã-His tagBackground : Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including negative regulation of extracellular matrix constituent secretion; regulation of nervous system development; and semi-lunar valve development. Acts upstream of or within several processes, including RNA destabilization; apoptotic signaling pathway; and negative regulation of inflammatory response. Located in membrane raft. Is expressed in several structures, including blood; dorsal aorta; extraembryonic component; genitourinary system; and liver. Human ortholog (s) of this gene implicated in several diseases, including Parkinsonism; acne; bone disease (multiple) ; glomerulonephritis (multiple) ; and lung disease (multiple) . Orthologous to human TNFRSF1B (TNF receptor superfamily member 1B) . Molecular Characterization: mass of 26.2 kDa after removal of the signal peptide. The apparent molecular mass of mTNFRSF1B-His is approximately 25-55 kDa due to glycosylation.Tag :C-6Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

P75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2

UniProt

P25119

Host

HEK293

Target Antigen

TNFRSF1B

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.