Canine IL31 Protein, His Tag

Description :Recombinant Canine IL31 protein with C-terminal6Ã-His tagBackground : IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]) .[supplied by OMIM, Mar 2008]Molecular Characterization: mass of 16.5 kDa after removal of the signal peptide. The apparent molecular mass of dIL31-His is approximately 15-25 kDa due to glycosylation.Tag :C-6Ãƒâ€”His tag

Product Specifications

Product Name Alternative

Interleukin-31?IL-31

UniProt

C7G0W1

Host

HEK293

Target Antigen

IL31

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.