Cynomolgus ROR2 Protein, N-His Tag

Description :Recombinant Cynomolgus ROR2 protein with N-terminal 10Ãƒâ€”His tagBackground : The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. Molecular Characterization: mass of 42.6 kDa after removal of the signal peptide. The apparent molecular mass of His-cROR2 is approximately 35-55 kDa due to glycosylation.Tag :N-10Ãƒâ€”His tag

Product Specifications

Product Name Alternative

BDB; BDB1; NTRKR2

UniProt

XP_005582291.2

Host

HEK293

Target Antigen

ROR2

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.