Cynomolgus CD3D and CD3E Heterodimer Protein, His Tag and hFc Tag

Description :Recombinant Cynomolgus CD3D Protein with C-terminal 10Ãƒâ€”His tag and Cynomolgus CD3E Protein with C-terminal human Fc tagBackground : T-cell surface glycoprotein CD3 delta and CD3 epsilon chain, also known as CD3D and CD3E or CD3D and CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.Molecular Characterization: mass of 10.9 and 37.0 kDa after removal of the signal peptide.Tag :C-10Ãƒâ€”His tag and C-Human Fc tag

Product Specifications

Product Name Alternative

CD3-DELTA; IMD19; T3D and IMD18; T3E; TCRE

UniProt

Q95LI8 and Q95LI5

Host

HEK293

Target Antigen

CD3D and CD3E

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.