Cynomolgus MICB Protein, His Tag

Description :Recombinant Cynomolgus MICB protein with C-terminal 10Ãƒâ€”His tagBackground : This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 33.4 kDa after removal of the signal peptide. The apparent molecular mass of cMICB-His is approximately 35-55 kDa due to glycosylation.Tag :C-10Ãƒâ€”His tag

Product Specifications

Product Name Alternative

MIC-B, PERB11.2

UniProt

A0A7N9DG75

Host

HEK293

Target Antigen

MICB

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.