Cynomolgus GUCY2C Protein, His Tag

Description :Recombinant Cynomolgus GUCY2C protein with C-terminal 10Ãƒâ€”His tagBackground : This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive) . Molecular Characterization: mass of 47.5 kDa after removal of the signal peptide.Tag :C-10Ãƒâ€”His tag

Product Specifications

Product Name Alternative

GCC; GC-C; HSER; STAR; DIAR6; GUC2C; MECIL; MUCIL

UniProt

G7PJX5

Host

HEK293

Target Antigen

GUCY2C

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.