Human APLNR Protein, hFc Tag

Description :Recombinant human APLNR Protein with C-terminal human Fc tagBackground : This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. Molecular Characterization: mass of 29.2 kDa after removal of the signal peptide. The apparent molecular mass of APLNR-hFc is approximately 35-55 kDa due to glycosylation.Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

APJ; APJR; HG11; AGTRL1

UniProt

P35414

Host

HEK293

Target Antigen

APLNR

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.