Human PEDF Protein, His Tag

Description :Recombinant human PEDF Protein with C-terminal6Ã-His tagBackground : This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. Molecular Characterization: mass of 45.2 kDa after removal of the signal peptide. The apparent molecular mass of PEDF-His is approximately 35-55 kDa due to glycosylation.Tag :C-6Ãƒâ€”His tag

Product Specifications

Product Name Alternative

OI6; OI12; SERPINF1; EPC-1; PIG35

UniProt

P36955

Host

HEK293

Target Antigen

PEDF

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.