Human APOE Protein, His Tag

Description :Recombinant human APOE Protein with C-terminal6Ã-His tagBackground : The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Molecular Characterization: mass of 35.1 kDa after removal of the signal peptide. The apparent molecular mass of APOE-His is approximately 25-55 kDa due to glycosylation.Tag :C-6Ãƒâ€”His tag

Product Specifications

Product Name Alternative

Apo-E; Apolipoprotein E

UniProt

P02649

Host

HEK293

Target Antigen

APOE

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.