Human PTH Protein, hFc Tag

Description :Recombinant human PTH Protein with C-terminal human Fc tagBackground : This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 35.6 kDa after removal of the signal peptide.Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

FIH1; PTH1

UniProt

P01270

Host

HEK293

Target Antigen

PTH

Purification

The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.