Human CRTH2 Protein, hFc Tag

Description :Recombinant human CRTH2 Protein with C-terminal human Fc tagBackground: This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]Description: Recombinant human CRTH2 Protein with C-terminal human Fc tagMolecular Characterization: CRTH2 (Met1-His33) hFc (Glu99-Ala330) Molecular Weight :The protein has a predicted molecular mass of 29.9 kDa after removal of the signal peptide. The apparent molecular mass of CRTH2-hFc is approximately 35-55 kDa due to glycosylation.Tag :C-Human Fc tag

Product Specifications

Product Name Alternative

DP2; DL1R; CD294; CRTH2; GPR44

UniProt

Q9Y5Y4

Host

HEK293

Target Antigen

CRTH2

Purification

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.