Human PLA2R1 Protein, His Tag

Description :Recombinant Human PLA2R1 Protein with C-terminal 10Ãƒâ€”His tagBackground : This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.Molecular Characterization: mass of 160.5 kDa after removal of the signal peptide. The apparent molecular mass of PLA2R1-10Ãƒâ€”His is approximately 130-250 kDa due to glycosylation.Tag :C-10Ãƒâ€”His Tag

Product Specifications

Product Name Alternative

CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R

UniProt

Q13018

Host

HEK293

Target Antigen

PLA2R1

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.