Human CDH17 (567-667) Protein, mFc Tag

Description :Recombinant human CDH17 (567-667) Protein with C-terminal mouse Fc tagBackground : This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. Molecular Characterization: mass of 37.1 kDa after removal of the signal peptide. The apparent molecular mass of CDH17 (567-667) -mFc is approximately 35-55 kDa due to glycosylation.Tag :C-mouse Fc tag