Human CD33 (18-259) Protein, His Tag

Description :Recombinant human CD33 (18-259) Protein with C-terminal 10Ãƒâ€”His tagBackground : Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. Molecular Characterization: mass of 28.2 kDa after removal of the signal peptide. The apparent molecular mass of CD33 (18-259) -His is approximately 35-55 kDa due to glycosylation.Tag :C-10Ãƒâ€”His tag

Product Specifications

Product Name Alternative

P67; SIGLEC3; SIGLEC-3

UniProt

P20138

Host

HEK293

Target Antigen

CD33

Purification

The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

Components

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization.

Storage Conditions

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.